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Much has been made of molecular mimicrythat is, the molecular similarity between a viral component for instance and an endogenous CNS protein leading to mistargeted autoimmunityin the pathogenesis of MS (Lang et al., 2002

Patient education and training for safe self-administration are critical, and gaps in support may impact adherence and outcomes

This returns the body to its previous state of defending a higher weight or set point, making weight regain highly likely without strong behavioral changes

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The prescribing information notes that gastrointestinal adverse effects are the most common reasons for treatment discontinuation