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Even modest weight reductions of 5-10% can restore normal menstrual function in some women with insulin resistance or PCOS, according to reproductive endocrinology research

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Finally, essential trace minerals like zinc and selenium are included to support the formation of metal-binding proteins and reduce the biological availability of toxic elements

Patients with specific genetic markers may experience accelerated weight loss or require lower doses to reach optimal satiety, reducing side effects and improving long-term adherence

The absence of reproductive toxicity data is the single largest knowledge gap

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