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A 10 mg dose sits in the middle of the typical treatment range, falling between the 5 mg maintenance dose and higher 15 mg options

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That is a widely reported pattern, not a rule

We did not conduct a meta-analysis for severe hypoglycaemia due to the absence of events in most treatment arms across all trials

For Donnelly, the issue is about more than numbers

This is why being careful does not save you here, and why the precision of the people in this market is so poignant