By highlighting industrial milestones and scientific frontiers, we aim to offer a comprehensive and forward-looking perspective on a field at the intersection of biology, engineering, and clinical practice, while critically examining current limitations in translation, manufacturing, and scalability
This result is particularly exciting for individuals at risk of developing type 2 diabetes
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Even now, more than 20 years later, and with increased knowledge about the biology of weight regulation, many clinicians feel that beyond advising their overweight patients to eat less and exercise more, there is little they can do
Collectively, these data support the conclusion that increased cellular GSSG accumulation in hepatocytes plays a critical role in the pathogenesis of NAFLD and may represent a potential therapeutic target for the treatment of NAFLD
