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Injectable glutathione has a very short half-life measured in minutes to hours and functions as acute antioxidant support, whereas tirzepatide is a weekly agent providing sustained metabolic signalling

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An additional hypothesis is that direct beta-cell to alfa-cell communication could be responsible for the glucagonostatic effect of GLP-1

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Although there is evidence that ghrelin and GLP-1 modulate reward responses in humans as well (Decarie-Spain & Kanoski, 2021), this has not been systematically reviewed before

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