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In addition to lowering the levels of blood glucose, as shown in Figure 1 , GLP-1RAs have also been shown to have a positive effect on multiple human tissues

Although no significant differences were found among the groups in total hip and femoral neck aBMD or trabecular bone score (TBS), changes in lumbar spine aBMD approached statistical significance

Another meta-analysis showed that HbA1c was reduced 2.1% and body weight 8.6kg with 15mg dose

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doi: 10.1089/dia.2011.0050 90 BushMAMatthewsJEDe BoeverEHDobbinsRLHodgeRJWalkerSEet al

GLP-1 analogues promote the conversion of glucose to glycogen in the liver and muscles, with UDP-Glucose being a precursor of glycogen