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2 Survey methodology Initially, we conducted searches using broad keywords, but found that directly using terms such as herb or Chinese herbal extracts could not accurately retrieve relevant literature

Write out every calculation with units included, verify reconstitution volumes with calibrated measuring tools rather than syringe markings, and document actual concentrations achieved rather than assumed values

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Interestingly, concomitant increases in metabolites related to methylated and oxidized waste products of nicotinamide were also observed in PBMCs, especially MeNAM, N -methyl-2-pyridone-5-carboxamide (Me2PY), and N -methyl-4-pyridone-5-carboxamide (Me4PY) [76] (Table 2)