In humans 200 mg/day of orally applied lactoferrin in combination with erythropoietin normalized the hemoglobin concentration in 75 cancer patients with anemia of chronic disease (Macci et al., 2010)
Seek immediate medical attention if anaphylaxis is suspected
Newer biologics represent progress
Research models with baseline HbA1c above 6.0% or fasting glucose above 110 mg/dL should not initiate this protocol without continuous glucose monitoring, as MK-677 specifically has been shown to increase fasting glucose by 58 mg/dL and HbA1c by 0.30.5% even in metabolically healthy subjects
Depending on the disease state of the population under study (e.g., preclinical, symptomatic, late-stage disease) and the objective of the intervention (prevention versus treatment), efficacy can be measured in different ways and commonly relies on the use of measures related to cognitive and functional outcomes, as well as changes in markers of pathobiology
No statement should be taken as healthcare advice
