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doi:10.1007/BF02253527

The Real Problem: Cytokine Activation According to the Purser Model, homocysteine is not the primary cause of tissue damage

Specifically, the peptide downregulates inflammatory genes including interleukin-1, tumor necrosis factor-, and nuclear factor-B, while upregulating protective genes such as those encoding antioxidant enzymes, DNA repair proteins, and extracellular matrix components

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This means your body has to rebuild the molecule from scratch, which is an inefficient process especially if your system is already under oxidative pressure

However, their overexpression on tumor cells results in over-activation of certain intercellular signaling pathways of proliferation, migration, and invasion of tumor cells