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Menopausal status is often missing in pharmacovigilance datasets and many trial summaries, yet it is a dominant effect modifier for vaginal symptoms via GSM

Oncogene 18 , 35933607 (1999)

Rhabdomyosarcoma of the head and neck in adults: MR and CT findings

Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis

Subcutaneous injections are also easier to self-administer, less painful, and lower-risk because the needle stays in a shallow, relatively avascular plane away from major nerves and vessels

Even "gentle" concentrations (10-20%) that would be well-tolerated on healthy skin pose significant risk