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In a controlled clinical trial, 16 gallstone patients scheduled for cholecystectomy were given 500 mg of supplemental vitamin C four times daily for two weeks before surgery

In particular, Xiaoming et al

L.HoR.WangX.et al

Additionally, glutathione converts darker eumelanin (found in pigmentation) into a lighter, yellowish form of melanin called pheomelanin, contributing further to a brightened skin effect