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Effect of Alpha-Lipoic Acid Supplementation on Endothelial Function and Cardiovascular Risk Factors in Overweight/Obese Youths: A Double-Blind, Placebo-Controlled Randomized Trial
And the answer was: better
This isnt a magic bullet GLP-1 drugs work, but theyre not without trade-offs: Gastrointestinal side effects : Nausea, vomiting, diarrhea affect users Muscle loss : Rapid weight loss can include lean muscle mass Rebound weight gain : Many patients regain weight after stopping treatment Long-term unknowns : We dont have 20-year safety data yet In India, where healthcare literacy varies widely, patient education and medical supervision will be critical
Do we require patients to use demonstrably less effective treatments
p=0.003) compared with placebo in 9,340 patients with T2D and a high risk of CVD