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Currently enrolling clinical trials (T1-DISCO and Obesity Complicating T1D: GLP-1 Analogue Anti-Obesity Treatment) in young adults living with T1D and obesity are investigating the impacts of GLP-1s on cardiovascular outcomes

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Recent clinical disappointments, including the discontinuation of investigational programs such as RMZ-035, ANG-3777, AP214, and GDC-8265, further underscore the complexity of the field