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The two main causes are ornithine transcarbamylase deficiency followed by type II citrullinemia

Menstrual changes during treatment may include longer or shorter cycles, heavier or lighter bleeding, or missed periods, typically related to the rate and magnitude of weight loss

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It has also been evidenced that obese IBD patients have shorter time to first surgery as well as lower quality of life in comparison with non-obese IBD sufferers (Singh et al

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