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1.2 Safety considerations and the limits of the GLP-1 analogy The success of GLP-1 receptor agonists should not obscure legitimate safety considerations associated with chronic peptide therapy
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New medications are in development, regulatory frameworks are being clarified, insurance coverage debates continue, and long-term outcome data accumulates
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We thank Robert Bok, MD, PhD, Romelyn Delos Santos, MD, Caroline Guglielmetti, PhD, and Tony Huynh, Hsin-Yu Chen, PhD for their assistance with experiments and helpful discussion