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Disease Prevention Pregnancy and early childhood developmental outcomes Supplementation during pregnancy Effect on pregnancy-associated conditions and neonatal outcomes The results of randomized controlled trials during pregnancy suggest that omega-3 polyunsaturated fatty acid (PUFA) supplementation does not decrease the incidence of gestational diabetes and preeclampsia (51-54) but may result in modest increases in length of gestation, especially in women with low omega-3 fatty acid consumption

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The metanalysis includes 5,323 patients (56-61 years) with T2D inadequately controlled (HbA 1c 7-10.5%), baseline BMI 23-45 kg/m 2 , mean diabetes duration of 9-12 years, and randomized to receive a GLP-1RA or GIP/GLP-1RA versus placebo in add on to basal insulin for at least 24 weeks (24-40 weeks)

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