At this level, GHK-Cu can potentially reach tissues and organs beyond the skin including joints, muscles, internal organs, and the central nervous system enabling the full spectrum of its gene-expression modulating activity
Still, theres promising evidence that the supplement may change the brain and nervous system in a way that helps lessen symptoms of: Major depressive disorder Schizophrenia Bipolar disorder Posttraumatic stress disorder (PTSD) Obsessive-compulsive disorder Trichotillomania (hair pulling) Substance use disorders Some studies show that the supplement may help ease symptoms of withdrawal, including a strong urge or craving to take drugs
Next, well look at some of the other active ingredients
In pulmonary fibrosis studies using bleomycin to induce lung injury in mice, GHK-Cu doses of 0.0026 to 0.26 mg/mL/day administered every other day reduced inflammatory cell infiltration, decreased interstitial thickness (the scarring that stiffens lung tissue), and lowered TNF-alpha and IL-6 expression
Because NAC and glutathione both contain sulfur, they can sometimes have a distinct smellthis is normal and actually a sign of the active compounds
One approach to acetylcysteine dosing was recently proposed by Hendrickson 2019