glutathione for skin whitening dosage lightening: a regnant myth or evidence-based verity? Glutathione for Skin Lightening: Safety

Steroid production in the skin is directly dependent on local enzymatic activity (e.g., aromatase), substrate availability, and mobilization of signal transduction and gene expression pathways, and can be modulated by several internal and external factors, including growth factors, inflammatory cytokines such as IL-1 and TNF, cAMP analogs, and glucocorticoids such as dexamethasone (Tkachenko et al., 2011

Ellmann GL (1959) Tissue sulfhydryl groups

A higher glutathione IV dosage is not automatically better or more effective

This high volume increases contamination risks without consistent sterile practices

[DOI] [Google Scholar] 192.Tluway F., Makani J

& Cooney, C