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The improvement effect of semaglutide on obese mice is partially driven by changes in serum metabolism and gut microbiota, as confirmed by fecal transplant experiments in this study

Notably, ICER complements the QALY with equal value of life years gained (evLYG) to address concerns that QALYs may undervalue extending life in very ill patients

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Cardiovascular efficacy of liraglutide and semaglutide in individuals with diabetes and peripheral artery disease