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[11] TMG can help replenish methyl groups and facilitate the clearance of nicotinamide, theoretically reducing the buildup of by-products that could cause fatigue or headaches in some individuals

Some of these change with tolerance

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1 min read Published on May 22, 2025 Written by EDGE Share this article What is Active B12

Patients taking metformin, those with gastrointestinal symptoms, older adults, or those with restricted diets should discuss B12 monitoring and potential supplementation with their GP