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(December 2013)

A pharmacokinetic study in rats found that oral administration produced substantial plasma concentrations, with a maximum concentration of 2252 ng/mL and an elimination half-life of approximately 6.9 hours

Each production lot is independently characterized using high-performance liquid chromatography (HPLC) and liquid chromatographymass spectrometry (LCMS) protocols

Whether this observation is solely the consequence of translocation of Parasutterella bacteria from the intestine to the EWAT or driven by more indirect mechanisms such as bacterially-produced metabolites 85 is yet to be determined

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