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In the adherent Rel3 cells treated with SU11274 we noticed increased expression of MUSASHI-1, which is considered as a marker of cancer stem cells (unpublished data)

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225,226 Therefore, the mechanism of action of GLP-1 RAs and a dual GLP-1/GIP RA can be characterized by modulating physiological properties within the model, enabling the prediction of altered pharmacokinetics for the affected drug

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