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Additionally, accumulation of free toxic compounds such as long chain fatty acid surrounding the mitochondria induces mitochondrial membrane permeability because of mitochondrial membrane depolarization and membrane canals formation

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Search terms included GLP-1 receptor agonist, diabetic retinopathy, glaucoma, age-related macular degeneration, ocular disease, and neuroprotection. The search included preclinical studies, large-scale retrospective cohort studies, and post-hoc analyses of major cardiovascular outcome trials (CVOTs)

But those benefits are largely contingent on long-term use and adherence

This is not just a marketing term

(2) mechanistic studies to determine biological plausibility