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R., Magness, S

Studies have demonstrated that FOXO proteins, including FOXO4, regulate oxidative stress responses and mitochondrial function, which are critical in neurological disorders

Scientific Reports

The main cerebral target for THC is type-1 cannabinoid receptors (CB1R), which are widely expressed in the brain and regulate various functions including neurotransmitter release, neuro-astroglial communication, and cellular bioenergetic processes [29,30,31,32]

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Future prospective research should evaluate this approach and should further refine the thresholds and dosing rates. Our Conclusions : The data presented highlights the potential for hepatotoxicity in patients with massive acetaminophen overdose despite timely treatment with NAC