Clinical trials have shown their potential in the treatment of idiopathic pulmonary fibrosis (IPF, 2018), 32 Alzheimers disease (AD, 2023, 2024, 2025), 33,34,35 diabetic macular edema (DME, 2024), 35 etc
Multiple cellular processes are considered to contribute to this functional decline and these are collectively referred to as the hallmarks of aging and these include processes like genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis 1
Ozempic EPAR overview
the key difference is MedVi's always-on availability
While conventional pharmaceutical and treatments are available, many synthetic drugs pose limitations or adverse effects, fueling growing interest in natural alternatives (391)
GLS1 inhibition using the small molecule CB-839 has demonstrated efficacy in alleviating BLM-induced pulmonary fibrosis [98, 100]