Microspheres demonstrate an increased binding capability compared to the homogenates
Results vary based on age, labs, health history, dosage, and consistency
Experimental Therapeutic Med 17:20912098 Desmoulin SK, Hou Z, Gangjee A, Matherly LH (2012) The human proton-coupled folate transporter: Biology and therapeutic applications to cancer
It ultimately addresses the research question:
Long-term overconsumption of B6 can cause severe neurological symptoms, skin lesions, sensitivity to light, nausea, and heartburn, with some of these symptoms occurring at intakes of 16 grams per day (17)
Protein binding is concentration-dependent and influenced by -1-acid glycoprotein concentrations, factors that may vary markedly in trauma, sepsis, pregnancy, and chronic disease