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Rather than simply co-administering two separate peptides, the team designed tirzepatide on the native GIP(1-42) backbone, then introduced specific amino acid substitutions at key positions to confer GLP-1 receptor cross-reactivity [6]

And in a non-related pharma side, think about what happened with baby formulas, right

The preclinical animal model data suggested that the glucose-lowering, lipid-lowering and insulin secreting effects were greater than those in GLP-1 receptor agonists [50]

What can we expect after Semaglutide treatment