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Glutathione is a naturally occurring antioxidant in the body, found in every cell

Simultaneously, IFN- disrupts the blood-brain barrier (BBB), thus facilitating the entry of peripheral inflammatory mediators into the CNS and contributing to neuroinflammation and neurological symptoms [48, 49]

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The decreased expression of TF in oligodendrocytes in the SN of PD patients may decrease the ability of oligodendrocytes to sequester excess iron, ultimately resulting in an increase in oxidative stress in dopaminergic neurons

[PMC free article] [PubMed] [Google Scholar] Akaike A., Takada-Takatori Y., Kume T., Izumi Y