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A 2025 Nature Medicine study of 200,000+ patients found: 2.02.5x higher risk of drug-induced pancreatitis Higher incidence of kidney stones and arthritis Chronic pancreatitis can permanently damage the pancreas and raises long-term cancer risk

95% CI 0.45 to 0.1

Keep your medication away from direct sunlight, protect pens with their caps on, and avoid leaving them in hot vehicles, as temperatures above 30C can degrade the active ingredient

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