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Wang YF, Wei W, Tangtanatakul P, Zheng L, Lei Y, Lin Z et al (2022) Identification of Shared and AsianSpecific Loci for Systemic Lupus Erythematosus and Evidence for Roles of Type III Interferon Signaling and Lysosomal Function in the Disease: A MultiAncestral GenomeWide Association Study

FIGURE 6 Panel A shows insulin secretion at basal glucose in response to 20 mM -OHB and concentration-dependent reversal with increasing NAC (n-acetyl cysteine)

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Most importantly, this animal model has predictive value as it demonstrates biomarkers of abnormal mitochondrial fatty-acid metabolism (that is, acyl-carnitine elevations) that could be used as routine biomarkers if found in children with ASD

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After 48 weeks treatment with two highest doses of retatrutide, 90% of participants had normalisation of liver fat [67]