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Therapy and Working Dogs: When the Environment Adds Load Therapy and service-adjacent dogs often carry a unique mix of demands: travel, unfamiliar environments, emotional intensity, and long periods of attentiveness

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This enzymatic action depletes the available intracellular pool of nicotinamide, directly limiting the synthesis of nicotinamide adenine dinucleotide (NAD+)

In the long-term, we still have to get more data to figure out how they interact and whether they'll ultimately be synergistic, says Dr