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Differential protein abundance by empirical Bayes was performed to identify proteins reaching statistical significance

Brunger, a Howard Hughes Medical Institute investigator, shares senior authorship of the study with Burton Dickey, MD, a professor of pulmonary medicine at the MD Anderson Cancer Center in Houston, and Manfred Frick, PhD, a professor of medicine at Ulm University in Germany

The researchers' revised "MINE 2" formula eliminates the fractional shortening percentage (FS%) because they have found that FS% "did not show independent association with cardiac outcomes in the current investigation." Therefore their simplified "MINE 2" formula is limited to three measurements -- LA/Ao, LVIDDn, and E-vel

These fluid shifts activate hearing cells in the cochlea (outer and inner hair cells which are the cells responsible for converting the mechanical energy of sound waves into electrical energy) and cause electrical signals to travel from the cochlea to the brain, thereby giving rise to the perception of sound

These approaches are minimally invasive, designed to support skin health, and are often chosen by those seeking a refreshed and brighter appearance