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This pilot study is asking whether new generation GLP-1 based highly effective anti-obesity medications (HEAOMs, semaglutide and tirzepatide) cause early changes in bone health during the first year of treatment, when weight loss tends to be most rapid

For example, one randomized trial showed that GLP-1 receptor drugs lowered HbA1c levels by ~2-3% and sustained the reduction out to 40 weeks

doi: 10.1016/j.anireprosci.2012.04.002 26 Department of Forestry, Fisheries and the Environment (DFFE)van der LingenC.DudleyS

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Staying hydrated, maintaining consistent meal timing, and avoiding sudden temperature shifts can help minimize chills while your metabolism adjusts to this new hormonal environment