study tested copper tripeptide serum specifically
doi: 10.1186/s13058-024-01834-5
When a very large dose of paracetamol is taken, glucuronidation capacity is saturated, more of the minor metabol ite is formed hepatic glutathione is deplete and this metabolite binds covalently to proteins in liver cells (and renal tubules) causing necrosis
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The most commonly reported effects with parenteral administration are transient flushing, mild nausea, and chest tightness during rapid IV infusion, all of which resolve by slowing infusion rate