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This medication is a safe option and should be part of clinicians arsenal to decrease cardiovascular risk in T2DM patients

that bone loss was most pronounced in weight-bearing skeletal sites, with no significant changes in non-weight-bearing areas such as the radius, suggests that mechanical unloading may be a key driver of bone resorption rather than a direct pharmacologic effect of GLP-1 receptor activation

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In comparison, the group taking the placebo only saw a weight loss of 2.4%

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Maddux: The SGLT2 inhibitors were drugs that have actually been on the market for about 10 years or so at this point