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Notably, inhibition of the NLRP3 inflammasome, which is primarily activated in macrophages and microglia (Gold and El Khoury, 2015

Samples were de-paraffinized and antigens unmasked by heating in a pressure cooker to 95C and 15 psi for 20 min in Trilogy alkaline solution with EDTA (Cell Marque), followed by 3 min in 90% formic acid

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Notably, one month after participants stopped taking the supplement, their levels began returning to baseline, indicating the need for continuous use