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Two Phase 2 trials were conducted concurrently: one in adults with obesity without diabetes, published in the New England Journal of Medicine in June 2023, and one in adults with type 2 diabetes, published simultaneously in The Lancet

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3 Mutagenicity studies conducted with amlodipine maleate revealed no drug related effects at either the gene or chromosome level

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Snigdha S, Ha K, Tsai P, Dinan TG, Bartos JD, Shahid M (2022) Probiotics: potential novel therapeutics for microbiota-gut-brain axis dysfunction across gender and lifespan