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Algahtani et al (134) proved the effect of nanoemulsion-based hydrogel of TQ 0.5% (w/w) on collagen fibers in mice with skin defects

However, studies with existing GLP-1RAs have shown discontinuation rates of up to 30% within 1 month, and up to 6070% within 12 months of initiation [14]

There is no human clinical data establishing a timeline for gut-specific effects

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