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Molecules 12 , 10451056

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As toxicologic pathologists sometimes experience difficulties in distinguishing the wide variety of liver lesions in the rodents for safety evaluation purposes, this document is a consensus of senior toxicologic pathologists regarding suggested nomenclature that should be used for specific lesions

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Long-Term Considerations While clinical trials up to 24 weeks demonstrate excellent safety, data on continuous use beyond 6-12 months remains limited