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Outcomes and follow-up The primary outcome was the composite of HFE and all-cause mortality

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Clinical trial protocols allowed for extended stays at any dose level when tolerability was an issue

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Both share a molecular structure built around a cobalt ion coordinated within a corrin ring, a structure chemically similar to the heme group in hemoglobin

Moreover, astrocytes contribute to lipid and ketone metabolism, playing a role in fatty acid oxidation, which supplies up to 20% of the adult brains energy needs 35