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This central action contributes to weight loss by reducing hunger and caloric intake

The therapy overcame the traditional reliance of PARP inhibitors on BRCA gene status for inducing resistance by synergistically activating apoptotic pathways, exacerbating DNA damage responses, and dually inhibiting the DNA repair system (114)

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PET scans are less useful for monitoring primary brain tumors or tumors that have spread to the brain from elsewhere in the body because the brain itself takes up a lot of glucose

Glucagon-like peptide-1 (GLP-1) drugs mimic the GLP-1 hormone, which helps control insulin and blood sugar levels, decreases appetite and slows digestion of food

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