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1998) analyzed CYP2A5 expression in C3H, C57BL/6, and B6C3F1 mice and found expression in phenobarbital promoted preneoplastic and neoplastic liver lesions in all three strains

The article names significant kidney or liver disease, diabetic retinopathy, and active gallbladder disease as needing careful evaluation before starting, on top of the contraindications it lists: personal or family history of medullary thyroid cancer and multiple endocrine neoplasia syndrome type 2

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This interdisciplinary approach combines principles from chemistry, biology, and engineering to develop innovative strategies for creating complex molecules with improved efficiency, selectivity, and sustainability