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Besides, polyphenols also influence other mechanisms which tend towards improvement of muscle performance, for instance mitochondrial biogenesis comprises of two methods, either stimulating stress-related cell signaling pathways, increasing expression of genes encoding cytoprotective proteins such as nuclear respiratory factor 2 (NRF2) where variants of the NRF2 gene have been associated with endurance performance, or modulating muscle function and mitochondrial biogenesis by upstream regulation of sirtuins (SIRT1) and peroxisome proliferator-activated receptor coactivator (PGC-1) activity (Somerville et al

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Retrieved May 12, 2021

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You've, uh, done how many high rocks is, uh, competitions, uh, two Marissa Liza: high rocks, Sam Rhee: two and multiple CrossFit competitions like you perform at a very high level

Some experts advocate for additional testing, such as parathyroid hormone levels, particularly in patients with bone disease or suspected vitamin D resistance