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Macrophage-secreted TGF-1 contributes to fibroblast activation and ureteral stricture after ablation injury

Soheilikhah, M

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Future research should focus on larger samples, alternative administration method (such as IV therapy), longer durations, and explore precursor-based therapies like N-acetylcysteine (NAC) that may support intracellular synthesis

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In other words, reliance on exogenous glutathione can induce metabolic complications or reduced endogenous production, as the bodys regulatory feedback mechanisms respond, which can cause more problems than the lack of ones own secretion and synthesis of glutathione