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[DOI] [PMC free article] [PubMed] [Google Scholar] 287.de Cosso L.F., Fourrier C., Sauvant J., Everard A., Capuron L., Cani P.D., Lay S., Castanon N

data from IQVIA

Toxicidad aguda y subcrnica : Estudios en rata a dosis hasta 1,000 g/kg (100 dosis efectiva) durante 30 das: sin alteraciones histopatolgicas, bioqumicas o hematolgicas significativas

and always consult your doctor before making any changes to your dosage

While this is usually a positive effect, such as reducing inflammation in blood vessels or other tissues, in rare cases, it might trigger localized inflammation in muscles or joints, which could lead to discomfort or stiffness in the neck

These changes reflect structural improvements from within rather than surface-level treatments