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The CagriSema combination uses 2.4 mg of cagrilintide with 2.4 mg of semaglutide, but reaching these doses requires coordinated titration of both agents

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IP3 stimulates Ca 2+ signaling and DAG acts through protein kinase C (PKC) leading to different cellular events, such as proliferation, growth and migration

The dose is then increased to 0.5 mg weekly, with possible further escalation to 1 mg or 2 mg weekly if needed for glycaemic control

Reducing the banana or peach portion can help keep the smoothie lighter