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10.1152/japplphysiol.00372.2013 17

24 Patients with subtype C disease have significant immune cell infiltration and proinflammatory features, especially a significant increase in the activity of immune cells such as lymphocytes and macrophages

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Immediate sample processing (centrifugation, plasma separation, freezing at 80C) is essential to prevent ex vivo peptide degradation

Moreover, a direct potential way could be the inhibition of presynaptic NMDA receptors and thus the activation of postsynaptic AMPA receptors by the release of glutamate