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Nonaka H, Ohue-Kitano R, Masujima Y, Igarashi M, Kimura I
Filed in 1992 and granted in 1997, these patents only listed Habener
Glucagon-like peptide-1: glucose homeostasis and beyond
Progression of retinopathy with glucagon-like peptide-1 receptor agonists with cardiovascular benefits in type 2 diabetes: a systematic review and meta-analysis
and 1-2 tbsp of healthy fats
Fmoc deprotection was achieved with 20% piperidine in DMF (twice for 2 min, room temperature, 300 rpm shaking) and peptide couplings were performed as double or triple couplings (twice for 5 min, 75 C, 300 rpm shaking, except for Arg and His, for which twice for 5 min, 50 C, 300 rpm shaking) consisting of AA/HCTU/DIPEA (ratio, 1:1.25:2.5) in fivefold excess compared to the resin
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