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Several large clinical trials have demonstrated that GLP-1 receptor agonists can reduce the risk of cardiovascular events, such as heart attacks and strokes, in people with type 2 diabetes who are at high risk for heart disease

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doi: 10.1371/journal.pone.0083314 184 Al-BadriMRAzarST

In preclinical models of glaucoma and DR, GLP-1RAs have demonstrated robust neuroprotective effects in ocular tissues, primarily by modulating oxidative stress, inflammation, mitochondrial function, and synaptic plasticity [42, 43]

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