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Current Available Treatments and Limitations Positive Airway Pressure Therapy Positive airway pressure (PAP) therapy remains the gold standard treatment for moderate to severe OSA, in which the patient wears a mask to sleep and a machine delivers a stream of air to keep airways open while sleeping

Exercise improves insulin sensitivity, cardiovascular health, and mental wellbeing whilst promoting gradual weight reduction

Berberine can enhance glucose lowering and may increase the risk of hypoglycemia when combined with insulin or insulin secretagogues

The tradeoff is that it produces a more constant GH stimulus rather than the natural pulse pattern sermorelin creates

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